Enzyme-triggered gelation: targeting proteases with internal cleavage sites
نویسندگان
چکیده
منابع مشابه
Enzyme-triggered gelation: targeting proteases with internal cleavage sites.
A generalizable method for detecting protease activity via gelation is described. A recognition sequence is used to target the protease of interest while a second protease is used to remove the residual residues from the gelator scaffold. Using this approach, selective assays for both MMP-9 and PSA are demonstrated.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2014
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c3cc48132h